Cardiac metabolic profiling in the fed state

Cardiac metabolic profiling in the fed state - CAMP

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON56735

Enrollment

198

Registered

2022-06-09

Start date

2022-08-18

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac nutrition / cardiac substrate metabolism

Interventions

Administration of peripheral parenteral nutrition (PPN) via a peripheral line. Determination of metabolites will be done via arteriovenous sampling from the already placed catheters.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adult (>18 years old) undergoing elective pulmonary vein isolation (PVI) Give verbral and written informed consent

Exclusion criteria

Exclusion criteria: Chronic renal disease with an estimated glomerular filtration rate (eGFR) 3x the upper limit of normal (ULN) Pregnancy or breastfeeding Insulin dependent diabetics Congenital metabolic disease Weight below 40 kg Inability to understand and read Dutch or English Known allergy or hypersensitivity to any of the non-investigational products in the study protocol Any other clinical condition that would jeopardize patients safety while participating in this trial, or may prevent the patient from adhering to the trial protocol.

Design outcomes

Primary

Measure	Time frame
Cardiac arteriovenous (A-V) gradient of metabolites, reflecting uptake and release of metabolites in the heart in the fed state.	—

Secondary

Measure	Time frame
To be determined metabolites	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)