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Comparing the effects of three PROtein-enhancement strategies on exercise-induced Muscle damage in Older adults

Comparing the effects of three PROtein-enhancement strategies on exercise-induced Muscle damage in Older adults - PROMO

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON56728
Enrollment
200
Registered
2024-05-01
Start date
2024-06-10
Completion date
Unknown
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inspanningsgerelateerde spierschade, sarcopenie exercise-induced muscle damage

Interventions

Participants will be randomly assigned to a protein-enhancement group or control group. Participants are instructed to consume 40g of supplement (30g of protein)/control powder per day for five week

Sponsors

Radboud Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - 60 years or older - Registered for the Nijmegen Four Days Marches (i.e., able to walk 30-50 km on consequtive days) - A habitual protein intake

Exclusion criteria

Exclusion criteria: - Allergic or sensitive for milk proteins, or lactose or gluten intolerant - Diagnosed type I or type II diabetes mellitus - Diagnosed intestinal diseases influencing the uptake of protein (i.e., active inflammatory bowel disease, Crohn*s disease) - Consumption of other freely available protein supplements during the study period. - If the subject intends to perform additional exercise bouts that cause muscle damage in the 4 days before the single- and multiple exercise bouts.

Design outcomes

Primary

MeasureTime frame
Circulating creatine kinase concentration is the primary outcome.

Secondary

MeasureTime frame
Secondary study parameters are circulating lactate dehydrogenase concentrations, muscle soreness, and muscle function.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)