De cognitieve prestaties van gezonde deelnemers thermal conditions ventilation
Conditions
Interventions
Each subject undergoes four conditions in randomized order. Two conditions
consist of poor air quality defined as 3000 ppm carbon dioxide and 23°C or 35°C
temperature, respectively. These two temper
Sponsors
Wählen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Adults between 18 to 40 years old Western-European background Generally healthy No medication which may influence the outcome parameters. This will be determined on a case-by-case basis. Contraceptive uses for women are allowed and will be verified through a questionnaire. Non-smokers or persons who quit smoking more than five years ago
Exclusion criteria
Exclusion criteria: • Participants, who do not want to be informed about unexpected medical findings, or do not wish that their treating physician will be informed, cannot participate in this study • Individuals with a diagnosed physical or mental disability or ADHD or depression • Any medication or medical condition that might interfere with the physiological outcome parameters or in some regards impair cognition • Unstable body weight (weight gain or loss >3kg in the past three months) • Participation in another biomedical study within 1 month prior to screening visit • Shift workers • Colour blindness • Pregnancy • People with a low haemoglobin or haematocrit concentration • Not having visited or resided in a warm country in the last 3 months • Participants with asthma or restricted lung function due to allergies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are the achieved scores of the cognition test, mainly derived from the CANTAB Cognition Test and the Cognitive Ability Task. | — |
Secondary
| Measure | Time frame |
|---|---|
| As secondary research objectives, it is additionally examined if humans perceive the air quality as less pleasant under the higher temperature, even if the air quality itself does not change in terms of carbon dioxide concentration. Also, the physiological reaction towards poor air quality and elevated temperature will be examined in isolation and interaction. Specifically, it will be investigated how these two factors affect the following physiological parameters: Capillary blood CO2 and pH level, salivary cortisol and alpha-amylase, blood cytokins serum concentration, lung function, heart rate, respiration rate, skin temperature, core temperature, blood pressure, physical activity, and metabolic rate. | — |
Countries
Netherlands
Outcome results
None listed