Connective TIssue Diseases rheumatic diseases Scar tissue formation in the lungs
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study as a patient, a subject must meet all of the following criteria: 1.Established diagnosis of: -SAD without ILD (according to the latest ACR-EULAR criteria) -SAD with ILD (according to the latest ACR-EULAR criteria and ILD diagnostics) -IPAF patients (according to latest consensus) [9] -IPF patients (according to latest diagnostics) [11] 2.Age >= 18 years 3. Providing informed consent after reading patient information.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: 1.No established diagnosis of SAD, IPAF or IPF. 2.Refusal to participate in the study. 3.Insufficient knowledge of the Dutch language.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our main study parameters will be IFN-I activation at baseline and after standard care immunosuppressants and relation between IFN-I and fibrosis in an in vitro model. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicable. | — |
Countries
Netherlands
Contacts
Public ContactT.M. Defesche
Erasmus MC, Universitair Medisch Centrum Rotterdam
Outcome results
None listed