Giant cell arteritis
Conditions
Interventions
Ultrasound for GCA with and without CEUS, SMI en 3D ultrasound. 
Sponsors
Ziekenhuis Groep Twente (ZGT)
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - patients and healthy controls 50 years or older - no atherosclerosis with ischaemic complications - sufficient understanding of the dutch language Specificaly for patients: - diagnosis RCA according to ACR/EULAR criteria 2022 - visible abnormalities consistent with RCA on conventional ultrasound sonography
Exclusion criteria
Exclusion criteria: - legal incapacity - use of corticosteroids for > 7 days at a dose of > 5 mg per day at the time of inclusion or in the month prior to the ultrasound - contraindication for the use of microbubbles or 3D ultrasound
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint will be the diagnostic value of the techniques, calculated using the sensitivity and specificity, including the AUC, the positive predictive value and negative predictive value. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary endpoints are the interobserver variability (calculated using Cohen's kappa dichotomous outcomes and the intraclass coefficient for continuous outcomes), and the duration in minutes. | — |
Countries
Netherlands
Contacts
Public ContactC Alves
Ziekenhuis Groep Twente (ZGT)
Outcome results
None listed