being overweight obesity being overweight obesity
Conditions
Interventions
Sponsors
Rijnstate
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - age between 18 and 65 years; - a 2 to 3 year postoperative period after bariatric surgery (gastric sleeve or Roux-and-Y bypass as primary surgery); - an umcomplicated procedure, and without symptoms of pain/nausea/etc; - normal weight loss (defined as total weight loss [TWL]: 25%
Exclusion criteria
Exclusion criteria: - Pre-existent oesophageal or gastric motility disorder, dysphagia, reflux, (postprandial) abdominal pain, neurological or metabolic conditions that significantly affect oesophageal or gastric motility; - When using proton pump inhibitors (PPI) or H2-antagonists, the inability to stop using them for 3 days; - Using opioids; - Previous oesophago-gastric surgery, other than bariatric surgery; - Unable to stop smoking for 24h; - Pregnancy or breast-feeding; - Patients with a drug or alcohol addiction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary objectives: - to define reference values for gastric scintigraphy using an optimised protocol (GE in T1/2 and retention); - to define reference values for oesophageal scintigraphy using an optimised protocol; - to describe SPECT/CT images and determine its benefit for anatomical correlation in asymptomatic (reference) and symptomatic population. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary objectives: - to explore the correlation of GE and oesophageal transit, and weight loss results or symptoms, using prospective data from this study and retrospective data from 53 symptomatic patients and similar studies previously (n=15, patients with RYGB) or currently (n = 24, patients with sleeve gastrectomy) performed in our centre, available for comparison. | — |
Countries
Netherlands
Contacts
Public ContactT Veerbeek
Rijnstate
Outcome results
None listed