abnormal spinal growth Scoliosis spinal deformity abnormal spinal curvature
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1. Females 2. 10-18 years of age 3. Diagnosis of AIS 4. 20-40° of coronal Cobb angle 5. No previous scoliotic brace or surgical treatment 6. Risser 0-2 7. pre-menarche or max 1-year post-menarche 8. Prescription of one of the following braces: Providence (night-time, UMCU), Chenau-type (full-time, Erasmus MC) 9. Written informed consent
Exclusion criteria
Exclusion criteria: 1. Any additional spine pathology 2. Non-idiopathic scoliosis (e.g. Syndromes associated with growth disorders, neuromuscular or connective tissue disorders) 3. contra-indication for MRI: vascular clips (absolute contra-indication), pacemaker and defibrillators (relative contra-indications), prostheses and other metal objects (due to risk of artifacts) 4. Claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Cobb angle correction in percentage (%) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Correction of Cobb angle of secondary curves - Correction of Apical vertebral rotation: relative to the sacrum - Change in Thoracic kyphosis: T4-T12. - Change in Lumbar lordosis: L1-S1 - Position, shape and volume of both the nucleus pulpous and annulus fibrosus. | — |
Countries
Netherlands
Contacts
Public ContactT.P.C. Schlösser
Universitair Medisch Centrum Utrecht
Outcome results
None listed