The 10-year follow-up of the ESCAPE trial: Do patients with a non-obstructive meniscal tear develop more knee osteoarthritis after knee surgery or after exercise therapy?

The 10-year follow-up of the ESCAPE trial: Do patients with a non-obstructive meniscal tear develop more knee osteoarthritis after knee surgery or after exercise therapy? - ESCAPE 10 year follow-up

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON56561

Enrollment

165

Registered

2023-11-20

Start date

2024-02-29

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis Joint wear

Interventions

Not applicable.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed with a non-obstructive meniscal tear 10 years ago who participated in the ESCAPE trial.

Exclusion criteria

Exclusion criteria: Not providing informed consent or indicated not to be approached for follow-up research.

Design outcomes

Primary

Measure	Time frame
The main study outcome will be the progression of osteoarthritis scored according to the MOAKS score. The MOAKS score is a new semi-quantitative scoring tool to quantify OA status based on MRI images. The degree of knee osteoarthritis is also assessed through X-ray images, using the Kellgren and Lawrence (KL) grading scale which evaluates knee osteoarthritis at 5 different levels, ranging from 0 (no osteoarthritis) to 4 (severe knee osteoarthritis). Furthermore, the progression of OA is also measured using the Osteoarthritis Research Society International (OARSI) Atlas sum score, ranging from 0 to 18 based on 6 items.	—

Measure

Time frame

The main study outcome will be the progression of osteoarthritis scored according to the MOAKS score. The MOAKS score is a new semi-quantitative scoring tool to quantify OA status based on MRI images. The degree of knee osteoarthritis is also assessed through X-ray images, using the Kellgren and Lawrence (KL) grading scale which evaluates knee osteoarthritis at 5 different levels, ranging from 0 (no osteoarthritis) to 4 (severe knee osteoarthritis). Furthermore, the progression of OA is also measured using the Osteoarthritis Research Society International (OARSI) Atlas sum score, ranging from 0 to 18 based on 6 items.

—

Secondary

Measure	Time frame
The secondary outcome measures of the study include knee function, pain, and quality of life, assessed through digital questionnaires (Patient-Reported Outcome Measures or PROMs). The following questionnaires will be utilized: - KOOS (Knee injury and Osteoarthritis Outcome Score) - EQ-5D (EuroQol-5 Dimension) - IKDC (International Knee Documentation Committee) - VAS Pain (Visual Analog Scale for Pain)	—

Measure

Time frame

The secondary outcome measures of the study include knee function, pain, and quality of life, assessed through digital questionnaires (Patient-Reported Outcome Measures or PROMs). The following questionnaires will be utilized: - KOOS (Knee injury and Osteoarthritis Outcome Score) - EQ-5D (EuroQol-5 Dimension) - IKDC (International Knee Documentation Committee) - VAS Pain (Visual Analog Scale for Pain)

—

Countries

Netherlands

Contacts

Public ContactA.J. Rasker

OLVG

a.rasker@olvg.nl020 599 2757

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jun 11, 2026