brain tumor primary brain tumor
Conditions
Interventions
The intervention consists of performing a training program called
high-intensity interval training which lasts for 12 weeks with two training
sessions per week. The training sessions will be perform
Sponsors
Amsterdam UMC
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - minimum age of 18 years; - reduced self-reported physical fitness, defined as a score of "average", "poor" or "very poor" on the first question of the International Fitness Scale (IFIS): "My general physical fitness is?"; - diagnosed with a primary brain tumor; - stable disease, i.e. no signs of radiological or clinical tumor progression; - no oncological treatment for at least two months prior to inclusion; - able to speak, read and write in Dutch.
Exclusion criteria
Exclusion criteria: - Karnofsky Performance Score
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is self-reported physical fitness, measured by the first question of the International Fitness Scale (IFIS), "Your general physical fitness is?" On a scale of 1 ("very poor") to 5 ("very good"). | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome measure is maximum oxygen uptake (objective physical fitness; VO2max), measured with a cardiopulmonary exercise test (CPET). In addition, a set of exploratory outcomes will be measured to examine the effects of the intervention. The measurements include a muscle strength measurement, MRI (optional), MEG (optional), neuropsychological assessment and various questionnaires. And last, focus groups will be planned to learn from patients perspectives of participating in high-intensity interval training. Last, we ask patients in the intervention and waiting-list control group to keep an exercise diary in the first three weeks and last two weeks of the intervention period, and the last two weeks of the follow-up period. | — |
Countries
Netherlands
Outcome results
None listed