Cardio-thoracale chirurgische aandoeningen Atelectasis collapsed alveoli
Conditions
Interventions
Participants will be randomly allocated into two groups. One group will have
their settings determined through Electrical Impedance Tomography (EIT)
measurements, while the other group will have the
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Elective Cardiothoracic surgery Older than 18 year
Exclusion criteria
Exclusion criteria: * Transplantation surgery * COPD GOLD III-IV * Pneumothorax without a chest tube. * Subcutaneous emphysema * Open chest * Chest wall abnormalities * Hemodynamic instability * Contraindications for inserting a nasogastric tube * Pacemaker or implantable cardioverter defibrillator (ICD)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference in PEEP levels between the baseline setting and the PEEP level established after a decremental PEEP trial using EIT or Pes measurement. | — |
Secondary
| Measure | Time frame |
|---|---|
| * Driving pressure at a tidal volume of 6 ml/kg IBW (Ideal Body Weight). * Dynamic compliance. * End-expiratory lung volume (EELV). * Global Inhomogeneity Index (GI). * Hemodynamic parameters (arterial blood pressure, heart rate, central venous pressure (CVP)). * P/F ratio (ratio of arterial oxygen tension to the fraction of inspired oxygen). * Transpulmonary pressures (end-expiratory transpulmonary pressure, end-inspiratory transpulmonary pressure, transpulmonary driving pressure). * Incidence of pneumonia, defined as received antibiotics with differential diagnosis of pneumonia, from day 2 till 5. | — |
Countries
Netherlands
Outcome results
None listed