Language and memory function in surgical patients with temporal lobe epilepsy

Language and memory function in surgical patients with temporal lobe epilepsy - EpiLang

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON56502

Enrollment

Registered

2023-09-08

Start date

2025-02-12

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy seizures epilepsy seizures

Interventions

The findings of&nbsp

this study will yield further insights into the organization of the language&nbsp

network after temporal lobe epilepsy surgery, including in relation to memory&nbsp

function.

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - Native speakers of Dutch; - 18 y.o. and older; - Undergone epilepsy surgery in the mesial temporal/ temporal lobe (left hemisphere); - At least 1 year after surgery; - Have seizures under control (combination of medication and surgery); - Have normal IQ and are able to provide informed consent

Exclusion criteria

Exclusion criteria: - Uncontrollable seizures; - Severe cognitive deficits post-surgery; - Neurological and psychiatric disorders (other than epilepsy); - Large and/or ferromagnetic metal parts in the head (except for a dental wire); - Implanted cardiac pacemaker or neurostimulator; - Claustraphobia; - Pregnancy; - Use of psychotropic or recreational drugs.

Design outcomes

Primary

Measure	Time frame
Main study parameter is the task-related brain activity measured with magnetoencephalography, together with patients' language and memory performance based on experimental and standardised tests.	—

Secondary

Measure	Time frame
-	—

Countries

Netherlands

Contacts

Public ContactV Piai

Radboud Universiteit Nijmegen

vitoria.piai@donders.ru.nl+31629646386

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jun 11, 2026