Immunological response after early extra and regular MMR immunization; 10 years follow-up

Immunological response after early extra and regular MMR immunization; 10 years follow-up - Early extra MMR immunization; 10 years follow-up

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON56402

Enrollment

Registered

2023-09-14

Start date

2023-10-30

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Measles infection paramyxovirus

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: • Participation in the study on the immunological effects of early extra measles vaccination, as described in a separate study protocol (NL45616.094.13/IIV-273) or participation in the BMR-nul questionnaire study • The parents/legally representatives accept participation in the trial according to the described procedures • Presence of an informed consent signed by both parents/legal representatives • Children must have received the MMR-2 vaccination

Exclusion criteria

Exclusion criteria: • Presence of a serious disease that requires medical care that can interfere with the results of the study • Known or suspected immunological disorder • Bleeding disorders

Design outcomes

Primary

Measure	Time frame
Measles specific serum IgG and virus neutralizing antibodies 2 years (+/- 2 months) after MMR-2 vaccination.	—

Secondary

Measure	Time frame
Serum IgG antibody concentrations against mumps and rubella 2 years (+/- 2 months) after MMR-2 vaccination.	—

Countries

Netherlands

Outcome results