None listed
Conditions
Interventions
Sensory stimuli will be applied during wake and sleep - including visual,
auditory, and tactile stimuli. These stimuli are well within the comfortable
range, and can be applied during sleep without
Sponsors
Netherlands Institute for Neuroscience
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: • Age 18-55 years • Good sleep quality (Pittsburg Sleep Quality Index
Exclusion criteria
Exclusion criteria: • Inability to follow procedures (eg due to insufficient knowledge of project language, cognitive or auditory impairments, etc.) • Individuals with known structural brain injury • Individuals with a history of epileptic seizures or suspected epilepsy • History or presence of a condition that may affect brain or sensory function or development; • History of a medical condition that may affect sleep and/or brain activity • History or presence of psychological/psychiatric conditions that may affect the subject's sleep and/or ability to follow experimental procedures; • Persons with substance abuse (alcohol or other substances) in the past 6 months • Nursing women or female subjects who are pregnant or planning to become pregnant. • Current or recent intake of medications with psychotropic effects (eg, antipsychotics, antidepressants, anxiolytics, psychostimulants, antihistamines, or beta-blockers - based on subject reporting and clinician judgment). • Insufficient sleep quality or irregular wake-sleep rhythm • Traveling to time zones with a time difference of more than 1 hour in the 2 weeks prior to the study days • Patients with extreme chronotypes (30 points or lower, or 70 points or higher on the Morningness-Eveningness questionnaire) • snoring
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) First part of the study: • EEG topographies and sources of modality-specific and supramodal responses • Differences in topographies at the scalp and source level and in trial-by-trial dynamics between evoked and spontaneous type I potentials 2) Second part of the study: • Correlation between the degree of sensory experience in the dream (visual, tactile, auditory) and the modality-specific component of the type I potential preceding the awakening (if present, result of first part of the study) • Correlation between the degree of surprise experienced in the dream and the supramodal component of type I potentials | — |
Secondary
| Measure | Time frame |
|---|---|
| • Differences in topographies at the scalp and source level and in trial-by-trial dynamics between type I potentials in sleep and wakefulness • Presence, latency and order of muscle activations recorded by EMG sensors in association with type I potentials • Presence and latency of pulse wave amplitude and heart beat variability changes associated with type I potentials | — |
Countries
Netherlands
Contacts
Public ContactFSR Siclari
Netherlands Institute for Neuroscience
Outcome results
None listed