Serologic surveillance of SARS-CoV-2 during the 2020 pandemic in exposed and unexposed healthcare workers in an academic hospital in Amsterdam

Serologic surveillance of SARS-CoV-2 during the 2020 pandemic in exposed and unexposed healthcare workers in an academic hospital in Amsterdam - Sero-surveillance SARS-CoV-2 in HCW

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON56239

Enrollment

864

Registered

2020-03-23

Start date

2020-03-23

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

corona COVID-19 SARS-CoV2

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Individual: a. health care personnel (physicians and nurses) from participating hospitals having (or expect within 4 weeks to have) direct patient contact with patients suspected for COVID-19 or with confirmed COVID-19 disease (exposure group) b. control group of health care personnel (administrative, policy and medical personnel without any patient contact) from participating hospital without direct contact with patients or contact with patients* direct environment (e.g. patient room, bed, instruments) (unexposed group) c: nurses and physicians in direct patiient care for non-COVID-19 patients 2. Informed consent; 3. Age >18 years

Exclusion criteria

Exclusion criteria: 1. Insufficient competency in Dutch to such an extent that it prevents sufficient comprehension of the participant information letter

Design outcomes

Primary

Measure	Time frame
- presence of SARS-CoV-2 antibody (IgM, IgG) titres	—

Secondary

Measure	Time frame
Presence of antibodies (IgG) to other corona-viruses Survey information about work conditions, exposures, infection symptoms. B and Tcell reactivity Immune response to vaccine Psychological signs and symptoms Impact of COVID-19 measures on mental health, resilience and job satisfaction.	—

Countries

Netherlands

Outcome results