myocardial infarction
Conditions
Interventions
None listed
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Myocardial infarction (chronic). The diagnosis myocardial infarction is based on clinical judgement and guideline definitions, such as complaints compatible with myocardial ischemia, ECG changes, cardiac troponin elevation. - Wall motion abnormalities in >=2 adjacent segments (on echocardiography) - Clinically referred for CMR (e.g. viability assessment) - Age 18-80 years of age
Exclusion criteria
Exclusion criteria: - Logistics: Inability to organize CT directly after CMR scan - Safety: pregnancy or breast-feeding - Safety: contraindications to CMR or CT * Metallic implant (vascular clip, neuro-stimulator, cochlear implant) * Pacemaker or implantable cardiac defibrillator (ICD) * Claustrophobia * Body weight >130 kg or BMI > 35 or body habitus that does not fit into the gantry * Contraindications to betablockers of nitrates - Safety: Renal failure (estimated Glomerular Filtration Rate (eGFR)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection of MI using spectral photon counting late enhancement (iodine/gadolinium) CT (extent, mass, percentage of left ventricle, transmurality) | — |
Secondary
| Measure | Time frame |
|---|---|
| • Correlation of infarct size measurement on CMR versus CT • Assessment of myocardial viability CMR versus CT • Assessment of kidney function after dual contrast infusion (eGFR/MDRD) • Detection of MI and CAD in a single CT scan | — |
Countries
Netherlands
Outcome results
None listed