Cervical radiculopathy neck herniation
Conditions
Interventions
Intervention: A personalized multimodal physical therapy program consisting of
neuromobilizations, cervical mobilizations, exercise, pain education,
behavioral therapy depending on the clinical find
Sponsors
Vrije Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with CR with an indication for surgery and no contra-indication for conservative management are eligible to participate. CR is diagnosed when the patient*s clinical presentation corresponds to relevant Magnetic Resonance Imaging (MRI) findings. An e-consult between the patients and the neurosurgeon will take place to verify the indication for surgery. Further inclusion criteria: Age >=18, at least 8 weeks of unilateral arm pain and/or paraesthesia, with arm pain intensity and/or paraesthesia intensity Numeric Pain Rating Scale (NPRS) >=4/10, sensory deficits, motor deficits and/or reduced reflexes.
Exclusion criteria
Exclusion criteria: Exclusion criteria: myelopathy, motor deficits measured by Medical Research Council (MRC) scale for muscle strength
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome for non-inferiority is disability over a 12-month period. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are arm and neck pain intensity, self-perceived recovery, fear of movement, treatment adherence, health-related quality of life, patient-specific activities, patient-acceptable symptom state, return-to-work, pressure, heat, cold tests (QST measurements), medication use, costs, percentages cross-overs, (re)surgeries, and complications. Additionally, transcriptomics of peripheral immune cells will be performed at baseline and 6 months follow up to compare gene expression profiles between patients who recover and those who do not. | — |
Countries
Netherlands
Outcome results
None listed