liver malignancy liver metastases metastasis in the liver
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: o Age >=18 years o Scheduled for liver resection (>=3 segments) at the MUMC+ o Able to understand the Dutch language sufficiently to give consent and follow orders during study assessments
Exclusion criteria
Exclusion criteria: o Cirrhotic liver, Child Pugh B-C o Unable or unwilling to perform CPET or indirect calorimetry o Liver ablation as the primary treatment o Termination of surgery due to too extensive oncological disease (open-close surgery)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the difference of energy expenditure pre- and postoperatively, as measured with doubly labelled water and indirect calorimetry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Additionally, aerobic fitness, physical activity level, metabolic factors in blood, and postoperative complications will be assessed. | — |
Countries
Netherlands
Contacts
Maastricht Universitair Medisch Centrum +