smoking addiction Tobacco use disorder
Conditions
Interventions
One group receives cTBS at the left insula, and the other group receives cTBS
at the right insula. Participants from both groups receive active and sham cTBS
for 20s each.
Sponsors
Amsterdam UMC
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Age of 18-30 year Females: use of a medically accepted form of hormonal birth control Smoking on average at least 10 filter cigarettes per day Smoking for at least one year Primarily smoking filter cigarettes and not any other form of tobacco
Exclusion criteria
Exclusion criteria: Previous experience with (deep) rTMS No reliable communication with the investigator or coping with the requirements of the experiment possible Last year or current psychiatric disorder diagnosis or treatment Suffering from a neurological disorder Possible alcohol dependence or drug (other than tobacco) use disorder diagnosis TMS contraindications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective cue-induced nicotine craving, measured by the Questionnaire on Smoking Urges score after a smoking cue-exposure task, and behavioural cognitive control, measured by the stop signal reaction time on the stop signal task. | — |
Secondary
| Measure | Time frame |
|---|---|
| Physiological cue-induced nicotine craving and cognitive control, measured by heart rate variability and skin conductance level. | — |
Countries
Netherlands
Outcome results
None listed