outbreaks viral infections
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: A) >18 years old B) Suspected infectious illness without a clear aetiology upon initial clinical evaluation C) Immunocompromised (Solid organ transplant recipient, OR received anti-C20 therapy in the past 9 months, OR primary immunodeficiency disorder) D) Symptom onset
Exclusion criteria
Exclusion criteria: A) Detection of a non-viral infectious agent that can explain the symptoms B) Surgery or Intensive Care admission in the last 30 days C Treatment with cytotoxic antineoplastic therapy in the last 30 days D) Symptoms of urinary tract infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Description of the clinical characteristics and aetiologies of infectious syndromes among the patients included in the POS; - Analysis of variations in local practices in diagnosis and treatment of Disease X among study sites; | — |
Secondary
| Measure | Time frame |
|---|---|
| - Characterization of intra-host viral evolution among immunocompromised patients with persistent viral infections; - Development of an infrastructure for prospective and systematic collection of data and clinical samples in a format that can be easily aggregated, tabulated and analysed across different participating centres; | — |
Countries
Netherlands
Outcome results
None listed