coronary artery disease coronary heart disease
Conditions
Interventions
None listed
Sponsors
Zuyderland Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Stable coronary artery disease OR Hemodynamically stable patients with a Non-STE Acute Coronary Syndrome Hemodynamically significant, diffuse LAD disease with involvement of the proximal segment (MEDINA 0.1.0 left main lesions allowed). Age >= 18. Signed informed consent. Ability to tolerate and no plans to interrupt relevant medical treatment during the duration of the study and willing to comply with protocol required follow-up.
Exclusion criteria
Exclusion criteria: Previous CABG Prior anterior myocardial infarction with clear evidence of residual akinesia and/or dyskinesia Extremely diseased LAD precluding intracoronary diagnostics or bypass grafting. Renal dysfunction (GFR
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease progression and plaque burden. Patients will undergo a CT scan at baseline and at 1-year follow-up in order to estimate coronary calcification with the Agatston score and to analyse the progressions of stenotic lesions with a not pre-specified selection of methods. | — |
Secondary
| Measure | Time frame |
|---|---|
| Graft patency. Patients undergoing CABG will receive a baseline and follow-up (at 1-year) CT scan. There is no pre-specified scanning protocol. | — |
Countries
Netherlands
Outcome results
None listed