Non-Invasive Portal and Hepatic Vein Pressure Estimation: MRI-Guided Diagnostics for Chronic Liver Disease

Non-Invasive Portal and Hepatic Vein Pressure Estimation: MRI-Guided Diagnostics for Chronic Liver Disease - NONEEDLES

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON56118

Enrollment

Registered

2023-11-20

Start date

2024-02-26

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end-stage liver disease liver cirrhosis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Eligable for liver transplantation (LT) screening - Age >= 18 years and 75 is a contraindication for LT) - Written informed consent

Exclusion criteria

Exclusion criteria: - Exclusion criteria for MRI (claustrophobia, pacemaker, metal implants, etc.) - A psychiatric, addictive or any other disorder that compromises the subjects ability to understand the study content and to give written informed consent for participation in the study

Design outcomes

Secondary

Measure	Time frame
Secondary objectives are cost effectiveness, safety, feasibility and efficacy of 4D flow MRI and CFD modelling.	—

Primary

Measure	Time frame
The aim of the study is to compare non-invasive PH measurement by 4D flow MRI and CFD modelling with HVPG measurements using the transjugular approach in patients with end-stage liver disease screened for OLT.	—

Countries

Netherlands

Outcome results