Evaluation of ablation lesions using cardiovascular magnetic resonance imaging

Evaluation of ablation lesions using cardiovascular magnetic resonance imaging - ENABLE-CMR

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON56080

Enrollment

Registered

2022-06-10

Start date

2023-03-08

Completion date

Unknown

Last updated

2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrialfibrillation afib

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Adult patients (age >=18 years old) - Paroxysmal or persistent AF, meeting criteria of the 2020 ESC Guidelines for diagnosis and management of atrial fibrillation - Patients scheduled to undergo catheter ablation for cardiac arrhythmia using one of the following techniques: - High power, short duration radiofrequency ablation - Ultra-low temperature cryoablation - Pulsed electrical field ablation

Exclusion criteria

Exclusion criteria: - Known (or suspected) allergic reaction to gadolinium - Contraindications for MRI (such as claustrophobia, certain implants, devices, high body mass index). - Pregnancy or breastfeeding - Prior intervention in the left atrium (ablation or surgery)

Design outcomes

Primary

Measure	Time frame
Incidence and length of gaps in isolation, measured on MR images, for different ablation modalities and strategies	—

Secondary

Measure	Time frame
- Additional ablation lesion characteristics measured on MR images (including total ablation lesion length, number of gaps in isolation, location of gaps in isolation, etc.) - Procedural characteristics (including ablation modality, ablation lesion location, ablation energy characteristics per ablation lesion, ablation lesion index, etc.) - Arrhythmia outcomes (including electrocardiographic documentation of atrial arrhythmia, arrhythmia burden on Holter monitoring, etc.) - Quality of life outcomes (AFEQT questionnaire)	—

Measure

Time frame

- Additional ablation lesion characteristics measured on MR images (including total ablation lesion length, number of gaps in isolation, location of gaps in isolation, etc.) - Procedural characteristics (including ablation modality, ablation lesion location, ablation energy characteristics per ablation lesion, ablation lesion index, etc.) - Arrhythmia outcomes (including electrocardiographic documentation of atrial arrhythmia, arrhythmia burden on Holter monitoring, etc.) - Quality of life outcomes (AFEQT questionnaire)

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Countries

Netherlands

Outcome results