LIMited wEdge ResectIon for Colonic T1 cancer - a prospective multicenter cohort study

LIMited wEdge ResectIon for Colonic T1 cancer - a prospective multicenter cohort study - LIMERIC-II

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55909

Enrollment

144

Registered

2022-07-04

Start date

2022-12-10

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T1 coloncarcinoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Lesion macroscopic suspect for T1 colon carcinoma during endoscopy (Hiroshima 2-3) o Or histologically proven T1 colon carcinoma • Size 25cm proximal from the anus (measured endoscopically) • > 18 years old

Exclusion criteria

Exclusion criteria: • Rectal carcinoma • Distant metastasis at baseline • > 50% circumferential growth of the lesion - Prior endoscopic resection or attempt, lifting not included

Design outcomes

Primary

Measure	Time frame
Reduction of oncologic resections for low-risk T1 colon carcinomas by using CAL-WR as primary treatment.	—

Secondary

Measure	Time frame
- Effectiveness (technically success and macroscopic- and microscopic R0 resection) of limited treatment approach - 3-year overall and disease free survival - 5-year overall and disease free survival - 30-day postoperative morbidity and mortality rate according to the Clavien-Dindo classification I-V - Total procedure related costs and cost effectiveness - Postoperative quality of life	—

Countries

Netherlands

Contacts

Public ContactJ. Hanevelt

Isala

j.hanevelt@isala.nl0637421727

Outcome results