Linking multimodal network imaging and cognitive functioning in glioma patients

Linking multimodal network imaging and cognitive functioning in glioma patients - Linking multimodal brain networks in glioma patients

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55895

Enrollment

275

Registered

2014-08-25

Start date

2014-10-29

Completion date

Unknown

Last updated

2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain tumor Glioma

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: (1) Adult (>= 18 years). (2) patients with suspected glioma based on radiological assessment and/or histopathologically confirmed WHO grade II-IV glioma. (3) written informed consent.

Exclusion criteria

Exclusion criteria: (1) Psychiatric disease or symptoms. (2) Other comorbidities of the central nervous system. (3) Insufficient mastery of the Dutch language. (4) Inability to communicate adequately.

Design outcomes

Secondary

Measure	Time frame
Secundary parameters are: • Cognitive performance on a standardized neuropsychological test battery and clinical parameters in terms of epilepsy and functional status. • Several cellular and molecular measurements derived from patients* tumor tissue in the subset of patients undergoing surgery. • Differences between multimodal neural network measures, and cognitive and clinical parameters derived from the longitudinal measurements.	—

Measure

Time frame

Secundary parameters are: • Cognitive performance on a standardized neuropsychological test battery and clinical parameters in terms of epilepsy and functional status. • Several cellular and molecular measurements derived from patients* tumor tissue in the subset of patients undergoing surgery. • Differences between multimodal neural network measures, and cognitive and clinical parameters derived from the longitudinal measurements.

—

Primary

Measure	Time frame
The main study parameters are MEG, resting-state fMRI, and DTI measures of connectivity and brain network topology.	—

Countries

Netherlands

Outcome results