Validity and reproducibility of practical performance-based tests to estimate aerobic capacity in patients scheduled for elective colorectal surgery

Validity and reproducibility of practical performance-based tests to estimate aerobic capacity in patients scheduled for elective colorectal surgery - Usefulness of practical tests to estimate preoperative aerobic fitness

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55879

Enrollment

Registered

2019-09-25

Start date

2020-02-21

Completion date

Unknown

Last updated

2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bowel cancer Colorectal cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in this study, a potential participant must meet all of the following criteria: - patients, males and females, >18 years of age, newly diagnosed with colorectal cancer (stage I-IV); - patients who undergo elective colorectal surgery at the Maastricht UMC+; - patients without contraindications for exercise testing (physical activity readiness questionnaire); - patients who gave informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: A potential participant who meets any of the following criteria will be excluded from participation in this study: - patients undergoing acute (emergency) surgery; - patients undergoing neoadjuvant therapy in the time between the usual preoperative screening of physical fitness (usual care) and the study visit; - patients with a medical status that contraindicates exercise or exercise testing; - patients with morbid obesity (body mass index >35 kg/m2); - patients who are unable to perform exercise testing at a cycle ergometer (for cardiopulmonary exercise testing and the steep ramp test), as well as patients who are unable to perform the 3-minute step test; - patients who are unable to cooperate with the testing procedures (e.g. insufficient understanding of the Dutch language).

Design outcomes

Primary

Measure	Time frame
The primary objective is to determine the criterion validity of the steep ramp test to estimate the ventilatory anaerobic threshold and oxygen uptake at peak exercise attained during maximal cardiopulmonary exercise testing in patients undergoing elective colorectal surgery, by evaluating the correlation of the primary outcome measure of the steep ramp test (achieved peak work rate) with the ventilatory anaerobic threshold and oxygen uptake at peak exercise as measured directly during cardiopulmonary exercise testing preoperatively in these patients.	—

Measure

Time frame

The primary objective is to determine the criterion validity of the steep ramp test to estimate the ventilatory anaerobic threshold and oxygen uptake at peak exercise attained during maximal cardiopulmonary exercise testing in patients undergoing elective colorectal surgery, by evaluating the correlation of the primary outcome measure of the steep ramp test (achieved peak work rate) with the ventilatory anaerobic threshold and oxygen uptake at peak exercise as measured directly during cardiopulmonary exercise testing preoperatively in these patients.

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Secondary

Measure	Time frame
The following secondary objective will be addressed for the purpose of obtaining more insight into the validity of the steep ramp test. The differences of scores of the steep ramp test between relevant patient subgroups will be tested to assess discriminative validity of the test.	—

Countries

Netherlands

Outcome results