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MicroRNA as biomarker for acute stroke

MicroRNA as biomarker for acute stroke - MicroRNA as biomarker for acute stroke

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON55785
Enrollment
430
Registered
2018-05-18
Start date
2018-11-07
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral hemorrhage cerebral infarction stroke

Interventions

None listed

Sponsors

Leids Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) Patients considered potentially eligible by EMS personnel for IVT/IAT for whom a pre- stroke alarm is initiated. 2) For patients included in the IS group: a National Institutes of Health Stroke Scale >=4 or eligible for reperfusion treatment 3) Age >=18 years 4) For patients included in the IS or HS group: clinical admission on the neurology ward

Exclusion criteria

Exclusion criteria: - Use of therapeutic heparin within 24 hours before onset of symptoms - Extracranial malignancy (patients can be included if they have a prior history of malignancy if the patient received curative treatment) - Alteplase treatment started

Design outcomes

Primary

MeasureTime frame
In-between differences in microRNA profiles on admission to the emergency department and within differences in each group in time.

Secondary

MeasureTime frame
clinical characteristics and radiological outcomes of the patients (all gathered in routine clinical practice)

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)