Cognitieve achteruitgang door veroudering cognitive complaints Cognitive decline mood complaints.
Conditions
Interventions
All intervention methods have a duration of two times three months. The three
months option will increase a priori motivation and lower the threshold to
participate. After the first three months, pa
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
65 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) between 65 years and 80 years of age; 2) native Dutch speakers; 3) functionally monolingual. That is, they should not use any language other than Dutch in their daily lives (they use the Dutch language 80% of the time); 4) not multilingual, although they may have learned additional (foreign) languages in their lives; 5) proficiency in the English language is below B1 level; 6) a current experience of self-perceived or informant-perceived persistent decline in cognitive capacity in comparison to his/her previously normal cognitive status which is unrelated to an acute event (as measured with the Subjective Cognitive Decline Questionnaire; score>5) 7) normal age-, sex-, and education-adjusted performance (>=23) on the Montreal Cognitive Assessment (MoCA); 8) participants should display normal intelligence (IQ>85) as assessed with the Dutch Adult Reading Test (DART); 9) they should be able to read 10) they should have access to a computer or tablet with internet connection and have basic skills using it as both interventions take place using an online format.
Exclusion criteria
Exclusion criteria: 1) a diagnosis of MCI, prodromal AD or dementia according to DMS-V criteria; 2) having extensive experience playing a musical instrument for the last 20 years; 3) a psychiatric or neurologic disease (apart from AD), medical disorder, medication, or substance use; 4) any current DSM-V disorders according to the SCID-I interview or a past diagnosis in the last 10 years; 5) any current or past alcohol or drug dependency or abuse; 6) daily use of benzodiazepines; 7) neurological problem (including epilepsy, dementia, neuromuscular disorders); 8) hearing or visual impairments other than correctable to normal by hearing devices or glasses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters concern i) cognitive flexibility; ii) brain activity in the theta band during switch tasks, and iii) changes in oxy- and deoxyhemoglobin concentration during switch tasks. Baseline characteristics and changes herein following foreign language training will be analysed. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters include clinical measures, measures of vulnerability for depression, quality of life and language proficiency. These measurements provide additional information to interpret and understand the effects induced by the language intervention vis-à-vis other forms of intervention and to understand the changes in neurocognitive functioning. | — |
Countries
Netherlands
Outcome results
None listed