Identification of the posterior lobe of the human pituitary gland during surgery using its electrophysiological, neural signature

Identification of the posterior lobe of the human pituitary gland during surgery using its electrophysiological, neural signature - Typing the electrophysiology of the human pituitary gland

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55741

Enrollment

Registered

2019-08-12

Start date

2020-12-10

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pituitary adenoma pituitary tumor

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Male and female patients undergoing transsphenoidal surgery for pituitary adenoma. - Identification of the posterior lobe on pre-operative MRI. This is most common in patients with microadenomas or small macroadenomas. - Age >18 years

Exclusion criteria

Exclusion criteria: - Emergency surgery - Cognitive impairments - Pregnancy - Pre-existing diabetes insipidus

Design outcomes

Primary

Measure	Time frame
Electrophysiological characteristics of different pituitary regions, i.e. firing patterns, voltages and frequency of spontaneous discharges. The following areas of the pituitary gland are of interest to us: the posterior pituitary lobe, central and lateral part of the anterior pituitary lobe, pituitary adenoma.	—

Secondary

Measure	Time frame
Durantion, outcome and complications of surgery	—

Countries

Netherlands

Outcome results