degeneration osteoarthritis
Conditions
Interventions
The intervention studied in the proposed project is the direct anterior
approach (DAA) for total hip replacement surgery. The DAA is compared to the
more standard used posterolateral approach (PLA).
Sponsors
Noordwest Ziekenhuisgroep
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Willing and able to participate in the study protocol; • Age between 18 and 80 years • ASA Physical Status I, II and III • Diagnosed with osteoarthritis of the hip • Subjects for who it is decided that they will undergo an uncemented THA at Northwest Clinics Alkmaar
Exclusion criteria
Exclusion criteria: • Patients with previous surgery to the ipsilateral or controlateral hip; • Patients with posttraumatic changes of the pelvis or femur; • Patients with inflammatory arthropathies; • Patients diagnosed with osteoporosis • Patients diagnosed with rheumatoid arthritis • Patients who suffer from insulin dependant diabetes • Patients who lack understanding of the Dutch language • Patients who are treated for or diagnosed with neurological or muscle disorders which make assessment of pain and gait not possible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional outcome parameters Disability, functioning during daily living, recreational activities and sports (Hip dysfunction and Osteoarthritis Outcome Score) will be assessed preoperatively and at 6 weeks, 3 months, 6 months, 12 months, and 24 months after surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical outcome parameters Perceived pain is assessed preoperatively and during the first 3 days after surgery (VAS pain). Length of hospital stay is registered. Quality of Life (EQ-5D), perceived pain and symptoms, and complications are assessed preoperatively and at 6 weeks, 3 months, 6 months, 12 months, and 24 months after surgery. Functional outcome parameters Quality of walking will be assessed preoperatively and at 1 year after surgery during a timed up and go test and a two times 50m walk using inertial sensors. Surgical outcome parameters Operation time, blood loss, and other relevant parameters in relation to the surgical procedures are registered. The cup and stem positioning are assessed using standard radiography in the first (hospital) days after surgery and at 1 year after surgery. A small subgroup of patients will undergo a CT or MRI scan. Cost-effectiveness Productivity costs, direct medical costs (costs of additional radiography, medical consumption) are assessed using questionnaires at 0, 3, 6, 9 and 12 months after surgery. | — |
Countries
Netherlands
Outcome results
None listed