EQUAL study

EQUAL study - EQUAL

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55640

Enrollment

500

Registered

2012-12-10

Start date

2013-07-15

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney failure

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Incident patients >=65 years with an estimated glomerular filtration of <= 20  ml/min/1.73m2 (based on MDRD) who have no history of transplantation or  dialysis.

Exclusion criteria

Exclusion criteria: Patients not able to give informed consent by themselves.

Design outcomes

Primary

Measure	Time frame
1. We will give a description of the progression of uremic signs and symptoms in patients. 2. The effects on survival and quality of life of dialysis start with a high renal function versus low renal function, dialysis start with a high number of symptoms and signs versus low number of symptoms and signs, and starting dialysis versus not starting dialysis will be investigated. 3.We will build models with values of kidney function derived from different methods that assess kidney function, i.e. serum creatinine-based measures like eGFR, 24-hrs urine collection-based measures, and tracer-based measures to develop a tool to assist clinicians in the decision when to start dialysis. 4.We will give a description whether patients were given information about the timing to start dialysis, whether patients were given information in which situations dialysis will be started, whether patients were given sufficient information about hemodialysis and peritoneal dialysis, whether patients had a preference to postpone dialysis or a preference for hemodialysis or peritoneal dialysis, and whether patients felt if they had influence on the decision making regarding the timing of initiation of dialysis. Furthermore, we will describe the reasons for the treating nephrologists why they started or not started dialysis yet in each patient. 5.We will give descriptions of renal Treatment Satisfaction Questionnaire scores for different subgroups.	—

Measure

Time frame

1. We will give a description of the progression of uremic signs and symptoms in patients. 2. The effects on survival and quality of life of dialysis start with a high renal function versus low renal function, dialysis start with a high number of symptoms and signs versus low number of symptoms and signs, and starting dialysis versus not starting dialysis will be investigated. 3.We will build models with values of kidney function derived from different methods that assess kidney function, i.e. serum creatinine-based measures like eGFR, 24-hrs urine collection-based measures, and tracer-based measures to develop a tool to assist clinicians in the decision when to start dialysis. 4.We will give a description whether patients were given information about the timing to start dialysis, whether patients were given information in which situations dialysis will be started, whether patients were given sufficient information about hemodialysis and peritoneal dialysis, whether patients had a preference to postpone dialysis or a preference for hemodialysis or peritoneal dialysis, and whether patients felt if they had influence on the decision making regarding the timing of initiation of dialysis. Furthermore, we will describe the reasons for the treating nephrologists why they started or not started dialysis yet in each patient. 5.We will give descriptions of renal Treatment Satisfaction Questionnaire scores for different subgroups.

—

Countries

Netherlands

Outcome results