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Platelet RNA as Biomarker for Delayed Cerebral Ischemia in Subarachnoid Hemorrhage

Platelet RNA as Biomarker for Delayed Cerebral Ischemia in Subarachnoid Hemorrhage - Biomarkers in Subarachnoid Hemorrhage

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON55603
Enrollment
630
Registered
2017-11-29
Start date
2018-06-26
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

subarachnoid haemorrhage, SAH, aSAH

Interventions

None listed

Sponsors

Amsterdam UMC
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Admission to Amsterdam UMC, location Meibergdreef Admission within <24h after symptom onset CT confirmed SAH  Age 18 years and older

Exclusion criteria

Exclusion criteria: Traumatic Subarachnoid Hemorrhage Patients with first blood collection >24hours after SAH Platelet isolation >12 hours of blood collection Patients who do not speak either English or Dutch

Design outcomes

Primary

MeasureTime frame
The difference in blood platelet RNA-profile between the study population and the control groups

Secondary

MeasureTime frame
the predictablity of functional outcome in mRS based on blood platelet RNA-profiles

Countries

Netherlands

Contacts

Public ContactM.A. Tjerkstra

Amsterdam UMC

m.a.tjerkstra@amsterdamumc.nl0650063414

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)