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Synovial immune alterations and biomarkers of arthritis

Synovial immune alterations and biomarkers of arthritis - Synovial immune alterations and biomarkers of arthritis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON55559
Enrollment
300
Registered
2013-07-23
Start date
2013-09-09
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

arthritis rheumatoid arthritis

Interventions

None listed

Sponsors

Academisch Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - 18 years or older - diagnosis of peripheral arthritis - active (drug resistant) inflammation of at least a (therapy resistant) knee or ankle joint.

Exclusion criteria

Exclusion criteria: patients unable to give informed consent

Design outcomes

Primary

MeasureTime frame
- to investigate pathogenic mechanisms in synovial tissue - to investigate these changes in the synovial tissue in relationship to the duration and different stages of inflammatory joint diseases - to investigate the relationship between these changes in the synovial tissue with changes in systemic immunity in different stages and forms of inflammatory joint diseases - to identify new therapeutic targets in the synovial tissue - to identify new diagnostic and prognostic markers in synovial tissue.

Secondary

MeasureTime frame
N.A.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)