Magnetic resonance imaging (MRI) for assessing fetal and neonatal brain development in the YOUth Cohort.

Magnetic resonance imaging (MRI) for assessing fetal and neonatal brain development in the YOUth Cohort. - Fetal and neonatal MRI.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55467

Enrollment

100

Registered

2016-11-09

Start date

2018-01-18

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hersen-, neurocognitieve- en gedragsontwikkeling behavior brain

Interventions

None listed

Eligibility

Age

No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Subject is included in the YOUth Cohor study, has a good understanding of the Dutch language and has signed informed consent.

Exclusion criteria

Exclusion criteria: Subject meets any of the exclusion criteria of the YOUth Cohort study. Subject and partner do not wish to be informed about unexpected fetal or neonatal MRI findings with therapeutic consequences. Subjects are not willing to provide informed consent. Subject experiences problems during the MRI scan or does not adhere to instructions of the MRI team.

Design outcomes

Primary

Measure	Time frame
A comprehensive examination of the developing brain will be carried out using T1, T2, DTI, SWI, PC-MRI and fMRI-derived (micro)structural and functional parameters: brain volumes, cortical thickness, cortical folding, white matter connectivity, hemodynamics and functional networks.	—

Secondary

Measure	Time frame
Structural and functional parameters of the developing brain will be linked to long-term neurocognition and behavioral outcome, i.e. behavioral control and social competence as examined in the YOUth Cohort.	—

Countries

Netherlands

Outcome results