Hepatocellular carcinoma/ primary liver cancer
Conditions
Interventions
Patients will undergo thermal ablation under general anesthesia as per usual. A
CT with intravenous contrast will be performed immediately before and after the
ablation, while the patient is under g
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 yrs or above 2. HCC very early (0) or early stage (A) according to the BCLC staging system Either de novo or recurrent HCC (prior locoregional therapy is allowed in the study) 3. Candidate for percutaneous thermal ablation as discussed in a multidisciplinary tumor board. Ablation as *bridge-to-transplant* is allowed in the study
Exclusion criteria
Exclusion criteria: 1. Estimated GFR
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients in whom reliable co-registration with MIRADA RTx of pre- and post-ablation CT images is feasible | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Inter- and intraobserver variability of CT-CT co-registration to determine the minimum ablation margin after thermal ablation for liver tumors 2. The time that is required for CT-CT co-registration 3. Percentage of local recurrence per group as categorized according to ablation margin: 5mm | — |
Countries
Netherlands
Outcome results
None listed