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Clinical aspects and molecular mechanisms in large granular lymphocyte (LGL) leukemia - IDeAL study

Clinical aspects and molecular mechanisms in large granular lymphocyte (LGL) leukemia - IDeAL study - Research into clinical aspects and molecular mechanisms in LGL leukemia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON55452
Enrollment
150
Registered
2018-07-05
Start date
2019-07-24
Completion date
Unknown
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blood cancer Large granular lymphocyte leukemia

Interventions

None listed

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with LGL leukemia / lymphoproliferation

Exclusion criteria

Exclusion criteria: No consent

Design outcomes

Primary

MeasureTime frame
Observational study without formal endpoints. At the end of this study, more insights will be gained about the following parameters: • fenotypical features • clonal TCR repertoire at DNA / RNA and possibly functional level • (epi)genetic and transcriptional patterns • (auto)antibodies and cytokines

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)