aortic valve stenosis heart valve restriction
Conditions
Interventions
The intervention group will undergo a limited acces aortic valve replacement
through ministernotomy, while the control group will undergo an aortic valve
replacement through full sternotomy. Both gr
Sponsors
Sint Antonius Ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Patients undergoing an aortic valve replacement for an aortic valve stenosis, defined as: o An aortic valve area of
Exclusion criteria
Exclusion criteria: - Inability to give written informed consent; - Patients requiring additional cardiac surgery during the same procedure; - Patients requiring a reoperation (of the aortic valve); - (relative) contraindications for a limited access approach; - Undergoing an emergency operation; - Recent myocardial infarction (
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main objective of the LIAR-Trial is to provide evidence on improving health status, quality of life and postoperative pain sensation after limited access aortic valve surgery, measured by multiple validated health questionnaires. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary objectives are aortic cross clamping time, cardio pulmonary bypass time, total operating time, technical success rate, complication rate, mortality rate, hospital length of stay, intensive care unit stay, reoperation rate, readmission rate and haemodynamic performance. | — |
Countries
Netherlands
Outcome results
None listed