refractory epilepsy
Conditions
Interventions
- Electrical stimulation via implanted leads
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Refractory epilepsy for at least one year, with a seizure frequency of at least four per month. * Failure of at least three adequately tried AED regimens, including ketogenic diet if appropriate. * Age 4 - 18 years at time of inclusion (first 3 patients 7 - 18 years old)
Exclusion criteria
Exclusion criteria: * Other progressive neurologic or medical diseases, including lesions on radioimaging * Evident co-existing non-epileptic seizures * Candidate for epilepsy surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Amount and severity of epilepsy | — |
Secondary
| Measure | Time frame |
|---|---|
| - Cognition corrected for age combined with assesment of behavior, development, daily life functioning and attention - EEG parameters - adverse events | — |
Countries
Netherlands
Outcome results
None listed