Examining brain phenotypes in carriers of (common) mutations in Polymerase gamma (PolG) using 7T MRI imaging.

Examining brain phenotypes in carriers of (common) mutations in Polymerase gamma (PolG) using 7T MRI imaging. - 7T fMRI in PolG carriers

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55367

Enrollment

Registered

2016-09-22

Start date

2018-04-10

Completion date

Unknown

Last updated

2025-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain structure, Mitochondrial disease

Interventions

&nbsp

collection of MRI data&nbsp

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria:  -Carrier of a POLG mutation -asymptomatic phenotype 

Exclusion criteria

Exclusion criteria:  -contra-indications for MRI -severe phenotype 

Design outcomes

Primary

Measure	Time frame
Biomarkers in non-symptomatic POLG subjects, including anatomical and/or functional differences.	—

Secondary

Measure	Time frame
NVT	—

Countries

Netherlands

Contacts

Public ContactM. Moerel

Universiteit Maastricht

michelle.moerel@maastrichtuniversity.nl+31-(0)-43-3881862

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)