cerebrovascular accident (CVA) stroke
Conditions
Interventions
None listed
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Early sub-acute ischemic or hemorrhagic stroke (2 weeks post-stroke) 2. First ever stroke 3. Diagnosed with moderate to severe unilateral arm-hand motor impairments (Fugl-Meyer Upper Extremity score
Exclusion criteria
Exclusion criteria: 1. Non-stroke related somatosensory and motor co-morbidity that may interfere with arm-hand function 2. Bilateral motor impairments 3. MRI contraindications (pacemaker, claustrophobia, vein clip, pregnancy, etc.) 4. Not able to understand or sign informed consent 5. Severe cognitive impairments and/or aphasia that interfere with the patient's ability to read or understand the study instructions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Action Research Arm Test (ARAT) will be used to assess patients* arm-hand skill performance capacity. Functional MRI will be used to assess the size of the functional finger representation in the primary somatosensory cortex. Diffusion MRI will be used to assess the integrity of somatosensory and motor white matter fiber tracts within the brain. | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed