Interaction between intestine and osteoarthritis of the hand and the effect of Sustained Release Calcium Butyrate

Interaction between intestine and osteoarthritis of the hand and the effect of Sustained Release Calcium Butyrate - Intestine, microbiome and osteoarthritis

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON55339

Enrollment

Registered

2021-11-30

Start date

2022-05-30

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoartritis of the hand

Interventions

Sustained Release Calcium Butyrate (600mg/day) for a period of 4 weeks

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: osteoarthritis of the hand

Exclusion criteria

Exclusion criteria: other chronic inflammatory diseases

Design outcomes

Primary

Measure	Time frame
compositional and functional characteristics of the microbiome.	—

Secondary

Measure	Time frame
change in intestinal barrier function, change in systemic inflammation parameters, immune tolerance and inflammatory response, tender joint count, pain, functioning of hands, patient*s global assessment, quality of life, stool behaviour.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)