Depression
Conditions
Interventions
All patients will receive weekly sessions of PCT during 8-weeks. PCT consists
of 8 weekly sessions of 60 minutes each, provided by trained and licensed
health care and clinical psychologists. The PC
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Does not meet the criteria of a current MDD episode according to the DSM-5, as assessed with the SCID-5-S; Is at least 8 weeks MDD diagnosis-free (with a maximum of 2 years); Has a HAM-D score of >=8 and
Exclusion criteria
Exclusion criteria: - Current (hypo)mania or a history of bipolar illness; - Any psychotic disorder; - Alcohol or drug misuse; - Primary Anxiety disorder diagnosis; - Electroconvulsive therapy in the previous 12 months; - Neurological disorder; - Disabling sensory and/or motor deficit.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameter will be assessed monthly during a one-year period after baseline assessment using the Inventory of Depressive Symptomatology (IDS-SR). | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary objectives are to investigate the effectiveness of PCT plus oNCRT, compared to PCT only, in patients partially remitted from depression on: Neuropsychological functioning (Verbal learning: immediate and delayed memory recall; Mental flexibility (inhibition and set-shifting ability); Verbal working memory; Planning) Positive and negative affect, dysfunctional attitudes, and stress Time to MDD relapse within a year from baseline Disability Health-related quality of life Health care and associated costs and costs from productivity loss | — |
Countries
Netherlands
Outcome results
None listed