cognitieve vermoeidheid Myasthenia Gravis
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: myasthenia gravis with anti-acetyl choline receptor antibodies
Exclusion criteria
Exclusion criteria: - A medical history of other active auto-immune disorders for which the patient currently receives a medical treatment, such as thyroid disease or rheumatoid arthritis. - A recent medical history of neoplasms. - Substance abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is a serum biomarker which correlates with levels of fatigue. We expect this biomarkers to be (partly) influenced by disease severity and treatment. Therefore this study has the option to include a longitudinal design (part II) with data and samples over the course of 6-12 months (2 visits). During this part II of the study fluctuations in fatigue will be related to fluctuations in the previously identified biomarkers. | — |
Secondary
| Measure | Time frame |
|---|---|
| We will collect information on depression scores, age, sex, BMI, medication and degree of physical activity as these factors are associated with fatigue and are likely to influence results. | — |
Countries
Netherlands
Outcome results
None listed