REcurrent LArynx tumor or Treatment Effects?

REcurrent LArynx tumor or Treatment Effects? - RELATE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55291

Enrollment

Registered

2020-10-28

Start date

2021-01-31

Completion date

Unknown

Last updated

2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laryngeal cancer Recurrent laryngeal and hypopharyngeal carcinoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Recurrent laryngeal or hypopharyngeal carcinoma after primary radiotherapy - Scheduled for salvage total laryngectomy - >=18 years of age - Given informed consent

Exclusion criteria

Exclusion criteria: - Patients who meet exclusion criteria for MRI at 3T as defined in the protocols of the radiology department - Patients with contraindication for CT contrast administration as defined in the protocols of the radiology department

Design outcomes

Primary

Measure	Time frame
The accuracy of DCE- and DWI-MRI based parameters based parameters in the differentiation of recurrent tumor tissue and radiation induced changes	—

Secondary

Measure	Time frame
Improvement of radiologists* delineation of tumor recurrences on imaging when given the results of this study. The accuracy of FDG-PET and CT based parameters in the differentiation of recurrent tumor tissue and radiation induced changes.	—

Countries

Netherlands

Outcome results