Brain tumor Glioma
Conditions
Interventions
BCBT consists of 5 patient-therapist contacts, either face-to-face, or via
video-consultation and information and assignments in 5 to 8 web-based therapy
modules delivered via an internet portal (Mi
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: a. >= 18 years of age b. histological diagnosis of primary brain tumor c. severely fatigued (CIS20 subscale subjective fatigue >= 35) d. stable disease, i.e. no oncological treatment for >= 2 months prior to inclusion e. expected survival >= 3 months f. no signs of radiological or clinical tumor progression g. no corticosteroid use h. exclusion of other causes of fatigue other than brain tumor treatment, such as anemia or infection i. able to speak, read and write Dutch j. having access to a computer with internet
Exclusion criteria
Exclusion criteria: a. depression b. primary sleep disorders c. current psychological treatment for a psychiatric disorder d. current pregnancy or having given birth in the past 3 months e. pharmacological treatment for fatigue that was started in the past 3 months (e.g. Amantadine, Modafinil, Ritalin, Pemoline) f. Karnofsky performance score
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue severity at 14 weeks after randomization as measured by the CIS20 subscale subjective fatigue will be the primary outcome. | — |
Secondary
| Measure | Time frame |
|---|---|
| The set of secondary study parameters, bearing potential to measure and predict treatment effects, will consist of questionnaires concerning quality of life and functioning, neuropsychological testing, neurological assesment, advanced neuroimaging and clinical parameters (tumor location, undergone previous treatments, medication use). The set of determinants, and primary and secondary outcomes will be measured at baseline and after the intervention at 14 weeks.. Ten weeks after the measurement the questionnaires will be completed again. | — |
Countries
Netherlands
Outcome results
None listed