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Single-handed, double loaded: The effect of an increase in biomechanical loads and central sensitization on the presence of musculoskeletal complaints in upper limb absence and brachial plexus injury.

Single-handed, double loaded: The effect of an increase in biomechanical loads and central sensitization on the presence of musculoskeletal complaints in upper limb absence and brachial plexus injury. - Single-handed, double loaded

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON55277
Enrollment
80
Registered
2019-12-11
Start date
2021-06-11
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal complaints overuse complaints

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Aged 18 and older - Able to give written informed consent - Able to read/understand Dutch or English - All questions of the Physical Activity Readiness Questionnaire (PAR-Q) answered with *no*, and therefore assuming that executing physical activities is reasonably safe. Or, when one of the questions is answered with *yes, if the subject can clarify that their clinician approved participation in the study or physical activity in general. If needed, and approved by the participant, the responsible clinician will be asked to approve participation in the study. Specific criteria per subgroup: - Upper limb absence (ULA): defect at transhumeral, transradial, elbow disarticulation or wrist disarticulation level, so the maximum voluntary contraction (MVC) protocol as part of the movement protocol can be executed. - Brachial plexus injury (BPI): a score between 0 and 8 on the questionnaire about functional movements of the hand, meaning almost no function in the hand. If a higher score is noted, an interview with the participant is held about sensation and function of the whole arm and not only of the hand. The expertise of the researchers will determine if the participant can be included. - In case of acquired ULA or BPI: >= 1 year after amputation or injury - Able bodied controls: matching based on gender and age group (+ or - 5 years) - Muskuloskeletal complaints (MSC): answered with *yes* on the first two questions (Controls: Q24-Q25, ULA Q32-Q33, BPI Q36-Q37) about MSC in the questionnaires for the participants. Having complaints like pain, stiffness and tingling of the muscles, bones, nerves and/or joints that are NOT the result of an accident, an infection, a sport injury or a joint disease, occurring for at least four weeks in the past year.

Exclusion criteria

Exclusion criteria: - Incapacity to follow instructions - Manifest co-morbidity, other than MSC, leading to restrictions in physical or mental functioning that interfere with the measurement results. Examples: fractures of the upper extremity bones, muscle dystrophies or stroke. - Lower extremity complaints, as the legs are used as a site reference in the Quantitative Sensory Testing (QST) Specific criteria per test: - QST: signs or suspicion of neurological dysfunction at tested sites - Capacity tests: history of medical disorder that influence heart rate or use of medication that influences heart rate (for example beta-blockers). If a participant uses medication to stabilize heart rate, they are asked to clarify if their clinician approves physical activity.

Design outcomes

Primary

MeasureTime frame
For the central sensitization protocol the main outcome measures are the Central Sensitization Inventory (CSI) questionnaire and the Quantitative Sensory Testing (QST) outcome measures. The primary outcome measures for the movement protocol are muscle fatigue, upper extremity angles, muscle activity and force.

Secondary

MeasureTime frame
Secondary study parameters are heart rate, the Borg CR10 scale and the functionality asssesed with the outcome parameters of the Jebsen Taylor Hand Function Test (JTHFT) and the Functional Capacity Evaluation for One-Handed individuals (FCE-OH).

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)