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AMersfoort COhort Study on functional decline, Healthy ageing and Frailty (AMCOHF): *Identification of physical predictors for healthy ageing and early stages of frailty in people from the age of 55 years: a prospective 10-year follow-up cohort study'

AMersfoort COhort Study on functional decline, Healthy ageing and Frailty (AMCOHF): *Identification of physical predictors for healthy ageing and early stages of frailty in people from the age of 55 years: a prospective 10-year follow-up cohort study' - AMersfoort COhort study on Healthy ageing and Frailty

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON55250
Enrollment
3000
Registered
2019-05-09
Start date
2022-06-23
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frailty Aging

Interventions

n.v.t.

Sponsors

SOMT University of Physiotherapy
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Subjects aged between 55 and 75 years, who are living independently in the city of Amersfoort (the Netherlands) and who understand spoken and written are eligible to participate. All participants will provide written informed consent. After signing informed consent, each participant will first undergo a medical screening by a physician in order to exclude any contra-indications for participation to the test battery. Those who are non-frail at baseline (i.e. robust on three frailty scales: score=0/5 for the Fried phenotype, score

Exclusion criteria

Exclusion criteria: Subjects who are at baseline unable to participate in the assessments due to physical (e.g. unable to stand up or walk) or cognitive impairments (e.g. unable to understand the test instructions and/or Mini Mental State Examination score

Design outcomes

Primary

MeasureTime frame
Variables: Factors related to trajectories of intrinsic capacity covering 7 physiological systems. Please see sections 6.1.2.1 to 6.1.2.7 of the research protocol for a desription of the physiological systems, the factors and the measurements. Primary outcome: Staying robust or the occurence of frailty when positive on at least one of three instruments (Fried Phenotype, Rockwood Frailty Index, Groningen Frailty Indicator). Please see section 6.1.1 of the research protocol for a description of these instruments for measuring frailty.

Secondary

MeasureTime frame
Additional explanatory variables: Factors related to functional ability and/or (neuro)physiological factors that can explain changes in trajectories of intrinsic capacity. Please see sections 6.1.3.1 to 6.1.3.6 of the research protocol for descriptions of these variables and their measurements.

Countries

Netherlands

Contacts

Public ContactA.M Berg

SOMT University of Physiotherapy

am.vandenberg@somt.nl0610050616

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)