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Decision-making for differently valenced stimuli in anorexia nervosa

Decision-making for differently valenced stimuli in anorexia nervosa - DecisionStimAN

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON55245
Enrollment
60
Registered
2021-04-15
Start date
2021-06-16
Completion date
Unknown
Last updated
2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia nervosa eating disorder

Interventions

None listed

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Age
16 Years to 64 Years

Inclusion criteria

Inclusion criteria: In order to be eligible for participation, subjects need to fulfill the following criteria: Anorexia Nervosa 1. >= 16 years of age 2. Be able to give informed consent 3. Able to speak, read and understand Dutch 4. Fulfill the DSM-5 criteria for anorexia nervosa 5. Have a BMI between 14 and 18.5 (16 - 18 yr. old participants have a BMI, that falls below the 5th BMI-for-age percentile) and/or currently undergo treatment for their anorexia. Healthy controls 1. 1. >= 16 years of age 2. Be able to give informed consent 3. Able to speak, read and understand Dutch 4. Have a BMI between 20 and 25 (16 - 18 yr. old participants have a BMI that falls between the 40th and the 85th BMI-for-age percentile) 5. Fall within one standard deviation of the Eating Disorder Examination Questionnaire mean norm scores for the respective comparison group 6. Like the taste of milk shake

Exclusion criteria

Exclusion criteria: Anorexia nervosa patients 1. A comorbid diagnosis of bipolar or psychotic disorder. 2. Use of psychotropic medication with a stable dosage for less than a month Healthy control participants 1. A current or past diagnosis of an eating disorder or another psychiatric disorder 2. Use of psychotropic medication For all participants 1. Visual problems if not corrected 2. Pregnancy 3. Chronic ear illnesses (e.g. tinnitus) 4. A known history of neurological disorders or injuries 5. Allergies or intolerances against the ingredients of the milkshakes

Design outcomes

Primary

MeasureTime frame
Characteristics of avoidance behaviors (i.e. frequency, velocity and directedness of avoidance decisions) and appetitive and aversive conditioned responses.

Secondary

MeasureTime frame
Valence ratings for the three outcomes (small portions of milkshake, aversive sounds, small monetary gain); symptoms of stress, depression and anxiety; sensitivity to reward and punishment.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)