Anorexia nervosa eating disorder
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible for participation, subjects need to fulfill the following criteria: Anorexia Nervosa 1. >= 16 years of age 2. Be able to give informed consent 3. Able to speak, read and understand Dutch 4. Fulfill the DSM-5 criteria for anorexia nervosa 5. Have a BMI between 14 and 18.5 (16 - 18 yr. old participants have a BMI, that falls below the 5th BMI-for-age percentile) and/or currently undergo treatment for their anorexia. Healthy controls 1. 1. >= 16 years of age 2. Be able to give informed consent 3. Able to speak, read and understand Dutch 4. Have a BMI between 20 and 25 (16 - 18 yr. old participants have a BMI that falls between the 40th and the 85th BMI-for-age percentile) 5. Fall within one standard deviation of the Eating Disorder Examination Questionnaire mean norm scores for the respective comparison group 6. Like the taste of milk shake
Exclusion criteria
Exclusion criteria: Anorexia nervosa patients 1. A comorbid diagnosis of bipolar or psychotic disorder. 2. Use of psychotropic medication with a stable dosage for less than a month Healthy control participants 1. A current or past diagnosis of an eating disorder or another psychiatric disorder 2. Use of psychotropic medication For all participants 1. Visual problems if not corrected 2. Pregnancy 3. Chronic ear illnesses (e.g. tinnitus) 4. A known history of neurological disorders or injuries 5. Allergies or intolerances against the ingredients of the milkshakes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Characteristics of avoidance behaviors (i.e. frequency, velocity and directedness of avoidance decisions) and appetitive and aversive conditioned responses. | — |
Secondary
| Measure | Time frame |
|---|---|
| Valence ratings for the three outcomes (small portions of milkshake, aversive sounds, small monetary gain); symptoms of stress, depression and anxiety; sensitivity to reward and punishment. | — |
Countries
Netherlands