Validation of Advanced Physiological MR Imaging Biomarkers

Validation of Advanced Physiological MR Imaging Biomarkers - ITEM (Imaging for Tumour Environment Map)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON55199

Enrollment

Registered

2020-04-09

Start date

2020-09-14

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain tumour

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Individuals of 18 years or older - Referred for surgery for resection or biopsy of brain tumour, including meningioma and glioma patients. - Referred for surgery for resection or biopsy of brain metastasis. - Written informed consent conform ICH-GCP

Exclusion criteria

Exclusion criteria: - Contra-indication for MRI (implanted metal parts, e.g. stents, vascular clips, pacemakers) - Inability to give consent

Design outcomes

Primary

Measure	Time frame
The correlation of advanced MRI biomarkers with proteomics or histopathological measurements of targeted biopsies in glioma.	—

Secondary

Measure	Time frame
Overall Survival (OS) and progression free survival (PFS).	—

Countries

Netherlands

Outcome results