Auditieve verbale hallucinaties Borderline. hearing voices. BPD verbal hallucinations
Conditions
Interventions
Participants will receive tDCS and sham treatment. For both tDCS and sham
patients have two daily appointments during 5 workdays.
Sponsors
Parnassia Bavo Groep (Den Haag)
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: To be eligible to participate in this study, a subject must meet all the following criteria: age 18 years or older, BPD confirmed with the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID II), AVH occurring at least weekly, capacity to consent and written informed consent for participation into this study from the patient. If they use antipsychotics, a stable dosage of antipsychotics the last month prior to inclusion is used as an additional criterion.
Exclusion criteria
Exclusion criteria: - Metal objects in or around the head that cannot be removed (i.e. cochlear implant, surgical clips, piercing) - History of seizures, or a history of seizures in first-degree relatives. - History of eye trauma with a metal object or professional metal workers - History of brain surgery, brain infarction, head trauma, cerebrovascular accident, broken skull, brain tumor, heart disease, cardiac pacemaker. - Skin disease on the scalp on the position of the tDCS electrodes - Coercive treatment based on a judicial ruling - Pregnancy in female patients. A pregnancy test will be used in cases of doubt, e.g. females of childbearing age who are sexually active but do not use any form of contraceptives. - Being diagnosed with a schizophrenia spectrum disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Voice Impact Scale (VIS), measure of distress caused by AVH | — |
Secondary
| Measure | Time frame |
|---|---|
| One frequency question, Visual Analogue Scale (2 items severity malevolence and omnipotence of the voices), Korte Klachten Lijst (Short symptom list, including item self-esteem and paranoid ideation), Brief State Paranoia Checklist, Quick Inventory of Depressive Symptomatology (QIDS), subscales of the Difficulties in Emotion Regulation Scale (DERS) and the Sheehan Disability Scale (SDS). Furthermore side-effects, smoking behavior and cognitive performance (Stroop test and trail making test) will be measured. One week after the tDCS intervention (tDCS and sham) several qualitative questions will be asked about the experiences with tDCS. | — |
Countries
Netherlands
Outcome results
None listed