brain aneurysm stroke
Conditions
Interventions
None listed
Sponsors
Haaglanden Medisch Centrum (HMC)
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Confirmed diagnosis of subarachnoid haemorrhage on CT-scan or lumbar puncture (in the presence of a negative CT-scan) - Age eighteen years or over at presentation.
Exclusion criteria
Exclusion criteria: - Subarachnoid haemorrhage deemed most likely of *perimesencephalic* origin after consideration of history, clinical examination and radiological findings (including angiographic imaging) - Subarachnoid haemorrhage deemed most likely of post-traumatic origin after consideration of history, clinical examination and radiological findings (including angiographic imaging) - Diagnosis of intracerebral arteriovenous malformations or dural arteriovenous fistula. - No diagnosis of intracranial aneurysm at six months after onset of symptoms. - Not mastering the Dutch language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is a standardised functional measurement, the score on modified Rankin scale after one year.. | — |
Secondary
| Measure | Time frame |
|---|---|
| Standardised functional outcome measurements: - modified Rankin scale after six months, two years, five years and ten years - extended Glasgow Outcome Scale after six months, one year, two years, five years and ten years Standardised cognitive status and mood/fatigue measurement: - Montreal Cognitive Assessment after six months, one year, two years, five years and ten years - Rancho los Amigos Levels of Cognitive Functioning Scale after six months, one year, two years, five years and ten years - Short form of the multidimensional Fatigue Syptom Inventory after six months, one year, two years, five years and ten years - Hospital Anxiety and Depression Scale after six months, one year, two years, five years and ten years Standardised measurement of quality of life and reporting of cost-effectivity: - EQ-5D and visual analogue scale after six months, one year, two years, five years and ten years - 36-question short form questionnaire after six months, one year, two years, five years and ten years - Quality Adjusted Life years and cost-utility analysis with patient reported costs through patient diaries Relation of complications of subarachnoid haemorrhages and their treatment with the outcomes above: - hydrocephalus and drainage of cerebrospinal fluid - delayed cerebral ischemia and its treatment - rebleeding and its treatment - recanalisation and its treatment Role of: - mobilisation and early rehabilitation in the hospital with the outcomes above - regional organisation of care, amongst others the referral area, with the outcomes above Prediction of outcomes above and occurrence of complications with clinical and radiological data from presenation | — |
Countries
Netherlands
Contacts
Public ContactWA Moojen
Haaglanden Medisch Centrum (HMC)
Outcome results
None listed